Week 2 is in our sights, headlined by a Thursday night clash between the Lions and the Bills in Buffalo.
Here are the lines for every Week 2 matchup at bet365 Sportsbook as of Sept. 14.
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Lions @ Bills
Spread: Bills -3.5
Moneyline: Bills -185, Lions +155
O/U: 53.5
Sunday, Sept. 20
Panthers @ Falcons
Spread: Falcons -1.5
Moneyline: Falcons -120, Panthers +100
O/U: 44.5
Bengals @ Texans
Spread: Texans -2.5
Moneyline: Texans -140, Bengals +120
O/U: 47.5
Browns @ Buccaneers
Spread: Bucs -8.5
Moneyline: Bucs -425, Browns +325
O/U: 40.5
Packers @ Jets
Spread: Packers -4.5
Moneyline: Packers -220, Jets +180
O/U: 45.5
Vikings @ Bears
Spread: Bears -5.5
Moneyline: Bears -250, Vikings +205
O/U: 48.5
Saints @ Ravens
Spread: Ravens -8.5
Moneyline: Ravens -425, Saints +325
O/U: 47.5
Eagles @ Titans
Spread: Eagles -7
Moneyline: Eagles -340, Titans +270
O/U: 39.5
Steelers @ Patriots
Spread: Patriots -5.5
Moneyline: Patriots -240, Steelers +195
O/U: 42.5
Jaguars @ Broncos
Spread: Broncos -2.5
Moneyline: Broncos -140, Jaguars +120
O/U: 43.5
Raiders @ Chargers
Spread: Chargers -7.5
Moneyline: Chargers -330, Raiders +265
O/U: 44.5
Dolphins @ 49ers
Spread: 49ers -12.5
Moneyline: 49ers -950, Dolphins +625
O/U: 46.5
Commanders @ Cowboys
Spread: TBD
Moneyline: TBD
O/U: TBD
Seahawks @ Cardinals
Spread: Seahawks -4.5
Moneyline: Seahawks -230, Cardinals +190
O/U: 41.5
Colts @ Chiefs
Spread: Chiefs -6.5
Moneyline: Chiefs -290, Colts +235
O/U: 48.5
Monday, Sept. 21
Giants @ Rams
Spread: TBD
Moneyline: TBD
O/U: TBD
