Headlined by a Sept. 9 Super Bowl rematch between the Seahawks and Patriots, as well as the NFL’s first-ever game in Australia between the Rams and 49ers, Week 1 is absolutely loaded.
Here are the lines for every Week 1 matchup at bet365 Sportsbook as of Sept. 8.
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Patriots @ Seahawks
Spread: Seahawks -3.5
Moneyline: Seahawks -180, Patriots +150
O/U: 44.5
Thursday, Sept. 10
49ers @ Rams (Australia)
Spread: Rams -3.5
Moneyline: Rams -190, 49ers +160
O/U: 48.5
Sunday, Sept. 13
Falcons @ Steelers
Spread: Steelers -3.5
Moneyline: Steelers -180, Falcons +150
O/U: 41.5
Ravens @ Colts
Spread: Ravens -3.5
Moneyline: Ravens -180, Colts +150
O/U: 47.5
Bills @ Texans
Spread: Bills -1.5
Moneyline: Bills -115, Texans -105
O/U: 44.5
Bears @ Panthers
Spread: Bears -3
Moneyline: Bears -165, Panthers +140
O/U: 47.5
Browns @ Jaguars
Spread: Jaguars -8.5
Moneyline: Jaguars -425, Browns +325
O/U: 40.5
Saints @ Lions
Spread: Lions -6.5
Moneyline: Lions -310, Saints +250
O/U: 49.5
Jets @ Titans
Spread: Titans -1.5
Moneyline: Titans -125, Jets +105
O/U: 39.5
Buccaneers @ Bengals
Spread: Bengals -3.5
Moneyline: Bengals -205, Buccaneers +170
O/U: 50.5
Cardinals @ Chargers
Spread: Chargers -9.5
Moneyline: Chargers -550, Cardinals +400
O/U: 47.5
Packers @ Vikings
Spread: Vikings -1.5
Moneyline: Vikings -125, Packers +105
O/U: 46.5
Dolphins @ Raiders
Spread: Raiders -3.5
Moneyline: Raiders -185, Dolphins +154
O/U: 40.5
Commanders @ Eagles
Spread: Eagles -4.5
Moneyline: Eagles -225, Commanders +185
O/U: 44.5
Cowboys @ Giants
Spread: Cowboys -2.5
Moneyline: Cowboys -160, Giants +135
O/U: 48.5
Monday, Sept. 14
Broncos @ Chiefs
Spread: Chiefs -2.5
Moneyline: Chiefs -150, Broncos +125
O/U: 43.5
