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    You are at:Home»Sports Trends»2025 CFP First-Round Odds: Oregon, Ole Miss Open as Huge Favorites
    Sports Trends

    2025 CFP First-Round Odds: Oregon, Ole Miss Open as Huge Favorites

    Ironside Sports MediaBy Ironside Sports MediaDecember 7, 2025No Comments2 Mins Read
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    Now that the College Football Playoff bracket is set, bettors are looking ahead to the odds for the first round of games.

    Notably, Ole Miss and Oregon open as massive, double-digit favorites over Tulane and James Madison, respectively. 

    The Bama–OU and Miami–Texas A&M matchups, according to the odds, could yield more competitive results.

    Let’s look at the odds at DraftKings Sportsbook as of Dec. 7.

    This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

    FRIDAY, DEC. 19

    No. 9 Alabama @ No. 8 Oklahoma (8 p.m. ET, ABC)

    Spread: Alabama -1.5
    Moneyline: Alabama -120, Oklahoma +100
    O/U: 41.5 points scored by both teams combined

    SATURDAY, DEC. 20

    No. 10 Miami @ No. 7 Texas A&M (noon ET, ABC)

    Spread: Texas A&M -4
    Moneyline: Texas A&M -175, Miami +145
    O/U: 52.5 points scored by both teams combined

    No. 11 Tulane @ No. 6 Ole Miss (3:30 p.m. ET, TNT)

    Spread: Ole Miss -16.5
    Moneyline: Ole Miss -950, Tulane +625
    O/U: 55.5 points scored by both teams combined

    No. 12 James Madison @ No. 5 Oregon (7:30 p.m. ET, TNT)

    Spread: Oregon -20.5
    Moneyline: Oregon -1650, James Madison +950
    O/U: 51.5 points scored by both teams combined

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