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Thursday Night Football opens Week 2 with an offensive clash between the Buffalo Bills and Detroit Lions. New users can use Underdog promo code FOXSORTS to get a $1K deposit match and unlock the Keep Your Millions promo before two of the NFL’s most explosive teams meet.
Buffalo’s offense looks to be one of the best again after the matchup after Josh Allen accounted for four touchdowns in the season opener. James Cook and DJ Moore are both major key pieces of the Bills’ attack. Detroit is coming off an overtime win against New Orleans, where Jared Goff connected with Amon-Ra St. Brown for two touchdowns and Jahmyr Gibbs found the end zone twice.
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- When: Thursday, September 17, 2026, 8:15 p.m. ET
- Where: Highmark Stadium, Orchard Park, NY
- Stream: Amazon Prime Video
- Boxscore: FOX Sports
Gamers to Watch
Buffalo’s offense already seems explosive, and Allen is the rationale Detroit has to arrange for chaos on each snap. Within the Payments’ Week 1 win, he threw for 320 yards and three touchdowns on 24 of 33 passing, then added a dashing rating as Buffalo piled up 41 factors and 470 complete yards.
Detroit allowed 30 factors in its opener, even whereas producing 5 sacks and three takeaways, so Allen’s job is to maintain pushing the tempo with out feeding that Lions entrance free possessions. Sustained drives and red-zone finishes give Buffalo its clearest path to controlling this Thursday evening recreation.
When Detroit leans laborious towards stopping the go, Cook dinner turns into Buffalo’s second hammer. He ripped off 115 dashing yards and a landing on 19 carries in Week 1, and the Payments averaged higher than 5 yards per rush as a workforce within the opener.
Detroit’s protection got here out aggressive with 5 sacks and three takeaways, the sort of entrance that may drive quarterbacks into long-yardage spots. A again who retains the offense on schedule and wins early downs takes stress off Allen and retains the Lions from teeing off all evening.
Detroit nonetheless has sufficient offensive stability to push Buffalo, and Goff’s decision-making decides whether or not the Lions keep within the shootout. In Week 1 he threw for 225 yards and a pair of touchdowns, finishing 23 of 32 passes whereas Detroit scored 30 factors.
Buffalo simply gave up 31 factors in its opener even whereas forcing 2 takeaways and recording 3 sacks, so the window is there if Goff stays clear. Timing throws and avoiding the empty drives that include detrimental performs preserve Detroit’s offense from stalling in opposition to a Payments protection that may nonetheless flip area place.
Goff’s Week 1 tone-setter within the passing recreation was St. Brown, and that connection is Detroit’s cleanest path to chunk performs right here. He caught 8 of 10 targets for 89 yards and a landing within the opener, working because the Lions’ major rhythm receiver.
Buffalo allowed 26 completions on 38 targets and 31 factors in Week 1, which places a premium on a receiver who can win early and end drives. St. Brown giving Goff a dependable outlet on intermediate routes helps Detroit keep forward of the chains in opposition to a Payments entrance that also generates stress.
