The San Francisco 49ers and Los Angeles Rams meet Thursday, Sept. 10, 2026, in a first for the league: a regular-season game at Melbourne Cricket Ground in Melbourne, Australia, with kickoff set for 8:35 p.m. ET.
The same team ended both of their 2025 seasons. Seattle routed the 49ers 41-6 in the divisional round, then beat the Rams 31-27 in the NFC Championship Game, one win short of Super Bowl LX. Los Angeles enters 2026 as the outright favorite to win Super Bowl LXI, at +500.
Below, we’ll give you all the details you need to know about how to watch this game.
How to Watch 49ers vs. Rams
- When: Thursday, September 10, 2026 at 8:35 p.m. ET
- Where: Melbourne Cricket Ground, Melbourne, Australia
- TV/Streaming: Netflix
Gamers to Watch
For Los Angeles, the clearest talent place title to observe is Puka Nacua as a result of his availability modified the form of this matchup. He was not listed on the Rams harm report launched Tuesday after coping with a core subject, and that factors to him being anticipated to deal with his normal function in opposition to San Francisco.
That issues in a recreation the place each groups enter 0-0 and there’s no 2026 manufacturing but to lean on. With the Rams nonetheless ready for normal season statistical leaders to emerge, Nacua stands out as a confirmed focus whose well being is likely one of the most related developments going into this opener. If he’s shifting freely, Los Angeles will get a significant piece of its passing recreation again at full power.
On the San Francisco facet, Christian McCaffrey is central as a result of the 49ers count on him to step proper again into his common function. He was not listed on Tuesday’s harm report after his standing had been watched by way of camp, and the newest replace factors to him being again at 100% for this opener.
In a Week 1 recreation with no 2026 crew manufacturing on the board but, that type of readability issues. San Francisco doesn’t have official statistical leaders established for the common season, so McCaffrey’s function turns into one of many strongest grounded indicators of the place the offense can circulate early. His involvement would give the 49ers their most reliable all function risk and a gentle solution to check the Rams from the opening collection.
If this turns right into a recreation the place San Francisco wants solutions over the center and on key downs, George Kittle turns into one of the vital necessary swing gamers to watch. He was listed as a restricted participant Tuesday due to an Achilles subject, however he has been practising repeatedly since coming off the energetic/PUP listing, and the door stays open for him to go well with up.
His watch worth comes from uncertainty tied on to this matchup. The 49ers know what his presence can do for construction, toughness, and quarterback consolation, however his standing continues to be one thing to trace proper as much as kickoff. A wholesome Kittle would give San Francisco one other main piece in a recreation that would hinge on which offense settles in first.
One of many extra fascinating below the radar Rams names is Terrance Ferguson as a result of his well being is settled even when his actual utilization will not be. He was not listed on Tuesday’s harm report after coping with soreness, which removes the quick concern heading into the opener.
What makes him price watching right here is the function query. The Rams have all 5 tight ends wholesome for Week 1, so his place within the rotation continues to be unclear, however he has generated buzz and enters this recreation accessible. In a season opener the place established 2026 manufacturing doesn’t exist but, gamers who can carve out a job shortly matter. If Ferguson earns significant snaps early, he may turn out to be a helpful change up piece within the Rams offense.
NFL Associated Tales
49ers vs. Rams Odds
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